What percentage of PCI procedures are associated with ISR?

• A. 5%
• B. 10%
• C. 15%
• D. 20%

Answer: (B)

In the context of percutaneous coronary intervention (PCI) procedures, in-stent restenosis (ISR) refers to the re-narrowing of an artery after it has been treated with a stent. This phenomenon is a significant concern following PCI as it can lead to further complications and the need for repeat interventions.

Research and clinical data indicate that ISR occurs in approximately 10% of patients who undergo PCI. This percentage reflects the historical rates observed before the widespread use of drug-eluting stents, which have helped reduce instances of ISR compared to bare-metal stents. Continued monitoring and advancements in stent technology have aimed to further lower the rate of ISR; however, the figure commonly accepted in many clinical guidelines and studies remains around the 10% mark.

Other percentages provided (5%, 15%, and 20%) either underrepresent or overrepresent the typical occurrence of ISR in PCI, based on current literature and clinical outcomes. Thus, the choice indicating that approximately 10% of PCI procedures result in ISR is widely recognized within the field.