What is a primary concern regarding non-compliance with DAPT?

• A. Increased cost of medications
• B. Higher incidence of stent failure
• C. Unpredictable drug metabolism
• D. Shorter hospital stays

Answer: (B)

The primary concern regarding non-compliance with dual antiplatelet therapy (DAPT) is that it can lead to a higher incidence of stent failure. DAPT is typically prescribed to patients who have undergone procedures such as coronary angioplasty and stenting to prevent thrombotic events, including stent thrombosis. Non-compliance with this regimen increases the risk of clot formation within the stent, leading to complications such as myocardial infarction and the potential need for re-intervention.

Stent failure can result from the buildup of thrombus if the antiplatelet agents are not taken as directed. Since the effectiveness of these drugs hinges on regular adherence, any lapses in medication can significantly compromise patient outcomes, making it a crucial factor in post-procedural care.